Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis
A. A. Alli, D. Desai, A. Elshika, L. Morel, M. Conrad, B. Proneth, W. Clapp, C. Atkinson, M. Segal, L. Searcy, N. Denslow, S. Bolisetty, B. Mehrad, Y. Scindia
This study shows ferroptosis occurs in kidney tubules of lupus nephritis patients and mice, and a drug can reduce it, suggesting new treatment options.
bioRxiv · May 26, 2022Immunology