Author

M. Segal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:fluorescence / live-cell microscopy· 4 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Ingargiola· 3 shared S. Weiss· 3 shared X. Michalet· 3 shared A. Gulinatti· 2 shared I. Labanca· 2 shared I. Rech· 2 shared M. Ghioni· 2 shared P. Maccagnani· 2 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiophysics

A. Ingargiola

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Author profile →

5 papers

Recent·Most cited

Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis

A. A. Alli, D. Desai, A. Elshika, L. Morel, M. Conrad, B. Proneth, W. Clapp, C. Atkinson, M. Segal, L. Searcy, N. Denslow, S. Bolisetty, B. Mehrad, Y. Scindia

This study shows ferroptosis occurs in kidney tubules of lupus nephritis patients and mice, and a drug can reduce it, suggesting new treatment options.

bioRxiv · May 26, 2022Immunology

Orderly assembly underpinning built-in asymmetry in the yeast centrosome duplication cycle requires cyclin-dependent kinase

M. Geymonat, Q. Peng, Z. Guo, Z. Yu, J. Unruh, S. Jaspersen, M. Segal

The paper shows CDK enforces Spc72 asymmetric docking and regulates nucleation site balance in yeast SPB duplication.

bioRxiv · May 22, 2020Cell Biology

High-throughput smFRET analysis of freely diffusing nucleic acid molecules and associated proteins

M. Segal, A. Ingargiola, E. Lerner, S. Chung, J. A. White, A. M. Streets, S. Weiss, X. Michalet

This paper introduces a high-throughput smFRET method using multispot excitation and SPAD arrays to rapidly analyze nucleic acid and protein conformations and interactions.

bioRxiv · Jun 25, 2019Biophysics

Optical crosstalk in SPAD arrays for high-throughput single-molecule fluorescence spectroscopy

A. Ingargiola, M. Segal, A. Gulinatti, I. Rech, I. Labanca, P. Maccagnani, M. Ghioni, S. Weiss, X. Michalet

The paper examines optical crosstalk in SPAD arrays used for high-throughput single-molecule fluorescence spectroscopy and finds it negligible and undetectable in data analysis.

bioRxiv · Nov 17, 2017Biophysics

48-spot single-molecule FRET setup with periodic acceptor excitation

A. Ingargiola, M. Segal, A. Gulinatti, I. Rech, I. Labanca, P. Maccagnani, M. Ghioni, S. Weiss, X. Michalet

This paper introduces a high-throughput smFRET system using 48 excitation spots and SPAD detectors, enabling rapid subpopulation identification and real-time kinetics studies.

bioRxiv · Oct 26, 2017Biophysics