ATP-Citrate lyase fuels axonal transport across species
L. Nguyen, A. Even, G. Morelli, R. Le Bail, M. Shilian, S. Turchetto, L. Broix, A. Brandis, S. Inbar, A. Chariot, F. Saudou, P. Dietrich, I. Dragatsis, B. Brone, J.-M. Rigo, M. Weil
The paper identifies ATP-citrate lyase (Acly) as a rate-limiting enzyme modulating Atat1 activity and α-tubulin acetylation, linking Elongator to axonal transport in projection neurons across species.
bioRxiv · Jul 7, 2020 · PreprintCell Biology