S. Remy

The paper develops a rat transgenic model with Foxp3-EGFP to study CD4+ and CD8+ regulatory T cells, revealing their frequencies, markers, suppressive activity, and transcriptome.

This study optimizes CRISPR/Cas9 reagent concentrations for efficient knockin in human iPS cells and rat embryos, achieving 50% knockin efficiency with reduced costs and toxicity.

The paper identifies a truncated variant of ASIC2b responsible for sodium retention in idiopathic nephrotic syndrome, independent of ENaC and aldosterone.

The paper shows TMEM176A/B ion channels are essential for dendritic cells to present antigens to CD4+ T cells, but not for Th17 or ILC3 function.

This study characterizes immune responses in a rat model of Duchenne’s disease and shows that anti-CD45RC antibody treatment improves muscle strength without side effects.