A neuronal relay mediates muscle-adipose communication that drives systemic metabolic adaptation to high-sugar diets
O. Kubrak, A. F. Joergensen, T. Koyama, S. Nagy, M. Lassen, J. Hald, D. Madsen, K. V. Halberg, M. J. Texada, J. L. Hansen, K. Rewitz
The paper identifies a muscle-neuronal-fat tissue axis that modulates insulin secretion and adipocyte sensitivity to high-sugar diets, preventing hyperglycemia.
bioRxiv · Aug 15, 2023 · PreprintPhysiology