Author

A. Federico

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 3 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Approach:statistical model· 4 Approach:deep learning· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

D. Greco· 4 shared A. Pavel· 3 shared A. Serra· 3 shared G. del Giudice· 3 shared M. Fratello· 3 shared L. A. Saarimaki· 2 shared S. Monti· 2 shared A. Di Lieto· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersPharmacology & Toxicology

D. Greco

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A network toxicology approach for mechanistic modelling of nanomaterial hazard and adverse outcomes

G. del Giudice, A. Serra, A. Pavel, M. Torres Maia, L. A. Saarimäki, M. Fratello, A. Federico, H. Alenius, B. Fadeel, D. Greco

This paper develops a network-based toxicology approach to model nanomaterial hazard by linking molecular changes to adverse outcomes in biological systems.

Advanced Science · Aug 1, 2024Peer-reviewedPharmacology & Toxicology

Beyond Basic Characterization and Omics: Immunomodulatory Roles of Platelet-Derived Extracellular Vesicles Unveiled by Functional Testing

M. Palviainen, J. Puutio, R. H. Ostergaard, J. A. Eble, K. Maaninka, J. Ndika, O. K. Kari, M. Kamali-Moghaddam, K. Kjaer-Sorensen, C. Oxvig, A. M. Aransay, J. M. Falcon-Perez, A. Federico, D. Greco, S. Laitinen, , P. R.-M. Siljander

This study investigates the immunomodulatory roles of platelet-derived extracellular vesicles by comparing their functional effects and omics profiles across different activation methods.

bioRxiv · Dec 31, 2023Cell Biology

Molecular annotation of AOPs guides the development of the next generation mechanistic chemical safety assessment and new approach methods

L. A. Saarimaki, J. Morikka, A. Pavel, S. Korpilahde, G. del Giudice, A. Federico, M. Fratello, A. Serra, D. Greco

This paper develops a framework to annotate Adverse Outcome Pathways (AOPs) using molecular data, enabling better integration of toxicogenomics into chemical safety assessment.

bioRxiv · Jul 8, 2022 · PreprintPharmacology & Toxicology

Computationally prioritized drugs inhibit SARS-CoV-2 infection and syncytia formation

A. Serra, M. Fratello, A. Federico, R. Ojha, R. Provenzani, E. Tasnadi, L. Cattelani, G. del Giudice, P. A. S. Kinaret, L. A. Saarimaki, A. Pavel, V. Cerullo, O. Vapalahti, P. Horvath, A. Di Lieto, , D. Greco

The paper identifies two compounds that inhibit SARS-CoV-2 infection and syncytia formation through computational prioritization and in vitro testing.

bioRxiv · Apr 15, 2021Pharmacology & Toxicology

animalcules: Interactive Microbiome Analytics 1 and Visualization in R

W. E. Johnson, A. Federico, T. Faits, S. Manimaran, S. Monti, Y. Zhao

animalcules provides an interactive R toolkit for analyzing 16S rRNA, shotgun metagenomics, and metatranscriptomics data with visualization and machine learning tools.

bioRxiv · May 29, 2020Microbiology

Yap suppresses T cell function and infiltration in the tumor microenvironment

E. Stampouloglou, A. Federico, E. Slaby, S. Monti, G. L. Szeto, X. Varelas

This study shows that Yap inhibits T cell function and infiltration in tumors, and its inhibition enhances anti-tumor immunity.

bioRxiv · Jun 5, 2019Cancer Biology