Author

P. Horvath

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 2 Bioengineering· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:bacteria (other)· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

A. Gacser· 2 shared C. Vagvolgyi· 2 shared M. Horvath· 2 shared R. Toth· 2 shared A. Beleon· 1 shared A. Carbonaro· 1 shared A. D. Davidson· 1 shared A. Di Lieto· 1 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

A. Gacser

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Unveiling the regulatory network controlling natural transformation in lactococci

F. Toussaint, M. Henry de Frahan, F. Poncelet, J.-M. Ladriere, P. Horvath, C. Fremaux, P. Hols

This study identifies key factors and regulators controlling natural transformation in Lactococcus lactis, revealing a unique regulatory network involving carbon/nitrogen sensors and the Clp degradation machinery.

PLOS Genetics · Jul 1, 2024Peer-reviewedMicrobiology

CometAnalyser: a user-friendly, open-source deep-learning microscopy tool for quantitative comet assay analysis.

A. Beleon, S. Pignatta, C. Arienti, A. Carbonaro, P. Horvath, G. Martinelli, G. Castellani, A. Tesei, F. Piccinini

CometAnalyser is an open-source deep-learning tool for automated comet assay analysis of fluorescent and silver-stained microscopy images, extracting quantitative features for DNA damage assessment.

bioRxiv · Jul 4, 2022Bioengineering

Multiparametric Platform for Profiling Lipid Trafficking in Human Leukocytes: Application for Hypercholesterolemia

S. G. Pfisterer, I. Brock, K. Kanerva, I. Hlushchenko, L. Paavolainen, P. Ripatti, M. M. Islam, A. Kyttala, M. D. Di Taranto, A. S. di Frega, G. Fortunato, J. Kuusisto, P. Horvath, S. Ripatti, M. Laakso, E. Ikonen

The paper develops a high-content imaging platform to quantify lipid trafficking in leukocytes, showing lipid mobilization correlates with LDL uptake and helps distinguish hypercholesterolemia cases.

bioRxiv · Apr 19, 2021Cell Biology

Computationally prioritized drugs inhibit SARS-CoV-2 infection and syncytia formation

A. Serra, M. Fratello, A. Federico, R. Ojha, R. Provenzani, E. Tasnadi, L. Cattelani, G. del Giudice, P. A. S. Kinaret, L. A. Saarimaki, A. Pavel, V. Cerullo, O. Vapalahti, P. Horvath, A. Di Lieto, , D. Greco

The paper identifies two compounds that inhibit SARS-CoV-2 infection and syncytia formation through computational prioritization and in vitro testing.

bioRxiv · Apr 15, 2021Pharmacology & Toxicology

Candida albicans enhances the progression of oral squamous cell cancrinoma in vitro and in vivo

M. Vadovics, N. Igaz, R. Alfoldi, D. Rakk, E. Veres, B. Szucs, M. Horvath, R. Toth, A. Szucs, P. Horvath, L. Tiszlavicz, C. Vagvolgyi, J. Nosanchuk, A. Szekeres, M. Kiricsi, , A. Gacser

This study shows that C. albicans promotes OSCC progression in vitro and in vivo by inducing inflammation, oncometabolites, and metastatic gene expression.

bioRxiv · Mar 31, 2021 · PreprintMicrobiology

Oral epithelial cells distinguish between Candida species with high or low pathogenic potential through miRNA regulation

M. Horvath, G. Nagy, N. Zsindely, L. Bodai, P. Horvath, C. Vagvolgyi, J. D. Nosanchuk, R. Toth, A. Gacser

The paper shows oral epithelial cells respond differently to C. albicans and C. parapsilosis, with miRNA regulation playing a key role in distinguishing their pathogenic potential.

bioRxiv · Jan 23, 2021 · PreprintMicrobiology

Neuropilin-1 is a host factor for SARS-CoV-2 infection

J. L. Daly, B. Simonetti, C. Anton Plagaro, M. Kavanagh Williamson, D. K. Shoemark, L. Simon-Gracia, K. Klein, M. Bauer, R. Hollandi, U. F. Greber, P. Horvath, R. B. Sessions, A. Helenius, J. A. Hiscox, T. Teesalu, , Y. Yamauchi

This study shows that SARS-CoV-2's S1 protein binds to NRP1 via the CendR motif, enhancing infection and identifying NRP1 as a therapeutic target.

bioRxiv · Jun 5, 2020Cell Biology

Structure of the native supercoiled flagellar hook as a universal joint

T. Kato, F. Makino, T. Miyata, P. Horvath, K. Namba

This paper reports the native supercoiled structure of the bacterial flagellar hook at 3.1 Å resolution using cryoEM single particle analysis, revealing its dynamic universal joint mechanism.

bioRxiv · Aug 27, 2019Biophysics