Molecular annotation of AOPs guides the development of the next generation mechanistic chemical safety assessment and new approach methods
L. A. Saarimaki, J. Morikka, A. Pavel, S. Korpilahde, G. del Giudice, A. Federico, M. Fratello, A. Serra, D. Greco
This paper develops a framework to annotate Adverse Outcome Pathways (AOPs) using molecular data, enabling better integration of toxicogenomics into chemical safety assessment.
bioRxiv · Jul 8, 2022 · PreprintPharmacology & Toxicology