ImmunologybioRxivPreprint
Cytotoxic CD4+ T cells in the bone marrow compromise healthy ageing by enhancing granulopoiesis
E. Gabande-Rodriguez, G. Soto-Heredero, E. Carrasco…·M. Mittelbrunn
This study identifies CD4+ cytotoxic T cells in the bone marrow that enhance granulopoiesis in aged mice, contributing to age-related diseases and showing that CCR5 inhibition can mitigate these effects.
DOI 10.1101/2024.01.26.577360