Cell BiologybioRxiv
Temporal landscape of mitochondrial proteostasis governed by the UPRmt
L. Uoselis, R. Lindblom, M. Skulsuppaisarn…·M. Lazarou
This study develops MitoPQ, a functional proteomics framework, to analyze how the UPRmt maintains mitochondrial proteostasis during stress and identifies oxidative phosphorylation as a key target.
DOI 10.1126/sciadv.adh8228