Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors
Z. Bakouny, D. A. Braun, S. A. Shukla, W. Pan, X. Gao, Y. Hou, A. Flaifel, S. Tang, A. Bosma-Moody, M. X. He, N. Vokes, J. Nyman, W. Xie, A. H. Nassar, S. Abou Alaiwi, , T. H. Ho
This study characterizes the molecular features and immune profile of sarcomatoid and rhabdoid renal cell carcinoma, showing their responsiveness to immune checkpoint inhibitors and identifying key genetic and transcriptional determinants.
bioRxiv · May 28, 2020Cancer Biology