G. Bouchard

Maternal body condition affects the response of larval spined toads' faecal microbiome to a widespread contaminant

The paper examines how maternal body condition influences the faecal microbiome response of larval spined toads to AMPA exposure.

The colocatome as a spatial -omic reveals shared microenvironment features between tumour-stroma assembloids and lung cancer specimens

The paper introduces the colocatome, a spatial-omic framework, to compare microenvironment features between tumour-stroma assembloids and lung cancer specimens, finding that fibroblasts protect cancer cells from treatment by reorganizing cytoarchitecture.

Multi-Omics Analysis of Fibroblasts from the Invasive Tumor Edge Reveals that Tumor-Stroma Crosstalk Induces O-glycosylation of the CDK4-pRB Axis

The paper analyzes multi-omics data from fibroblasts at the tumor edge and core to show O-glycosylation of the CDK4-pRB axis is induced by tumor-stroma crosstalk.

Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma

This study characterizes translocation renal cell carcinoma (tRCC) through integrated clinical and molecular analysis of 152 patients, identifying key features like MiT/TFE fusions, NRF2-driven antioxidant response, and differential treatment outcomes.

Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors

This study characterizes the molecular features and immune profile of sarcomatoid and rhabdoid renal cell carcinoma, showing their responsiveness to immune checkpoint inhibitors and identifying key genetic and transcriptional determinants.