Preclinical characterization of immune responses induced by a candidate gonococcal native Outer Membrane Vesicle vaccine
Ilaria Onofrio, Sthefany Pagliari, A. Francis, Molly E Quinn, Thomas Belcher, Senuri N. Dissanayake, Clement Twumasi, Iason Vichos, Lukasz A. Grudzein, Christine S. Rollier, Calman Alexander MacLennan
This study evaluates the immunogenicity of a gonococcal outer membrane vesicle vaccine (GonoVac) in mice and rabbits, showing it induces stronger serum and vaginal antibodies and bactericidal activity compared to 4CMenB.
mSphere · Jun 22, 2026Peer-reviewedImmunology