Author

A. G. Sainz

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. E. Cress· 1 shared A. L. Casillas· 1 shared A. N. Clements· 1 shared C. C. Jensen· 1 shared C. K. Miranti· 1 shared N. A. Warfel· 1 shared P. R. Langlais· 1 shared R. K. Toth· 1 shared

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2021-2021 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. E. Cress

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1 paper

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedJul 2, 2021

Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

A. L. Casillas, S. S. Chauhan, R. K. Toth…·N. A. Warfel

This study identifies PIM1 kinase as a regulator of HIF-1α stability and angiogenesis in solid tumors through direct phosphorylation at threonine 455.

DOI 10.1038/s41388-021-01915-1

humanexperimental assay

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