Cell BiologybioRxiv
Identification of the Global miR-130a Targetome Reveals a Novel Role for TBL1XR1 in Hematopoietic Stem Cell Self-Renewal and t(8;21) AML
G. Krivdova, V. Voisin, E. M. Schoof…·E. R. Lechman
This study identifies miR-130a as a regulator of HSC self-renewal and differentiation, with TBL1XR1 as a key target, and shows its role in maintaining the oncogenic program in t(8;21) AML.
DOI 10.1016/j.celrep.2022.110481