BiochemistrybioRxiv
One-shot design elevates functional expression levels of a voltage-gated potassium channel
J. J. Weinstein, C. Saikia, I. Karbat…·S. J. Fleishman
The paper introduces mPROSS, an algorithm that improves the functional expression of membrane proteins through one-shot design, achieving up to 14-fold increase in current densities without altering single-channel activity.
DOI 10.1002/pro.4995