Author

A. Harmelin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

E. Shema· 2 shared G. Ron· 2 shared L. Fellus-Alyagor· 2 shared N. Furth· 2 shared N. London· 2 shared R. Oren· 2 shared A. C. Kotze· 1 shared A. Plotnikov· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

E. Shema

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas

D. Algranati, R. Oren, B. Dassa, L. Fellus-Alyagor, A. Plotnikov, H. Barr, A. Harmelin, N. London, G. Ron, N. Furth, E. Shema

This study investigates dual targeting of HDACs and MYC in H3-K27M pediatric gliomas, showing synergistic effects in reducing cell viability and tumor growth.

bioRxiv · Feb 5, 2024Cancer Biology

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

N. Harpaz, T. Mittelman, O. Beresh, O. Griess, N. Furth, T. M. Salame, R. Oren, L. Fellus-Alyagor, A. Harmelin, S. Alexandrescu, J. G. Marques, M. G. Filbin, G. Ron, E. Shema

The paper uses CyTOF to analyze histone modifications in DIPG tumors, identifying two epigenetically distinct subpopulations with differential proliferation and marker expression.

bioRxiv · Nov 2, 2021Cancer Biology

Time-Space Fourier κFormula Filter for Motion Artifacts Compensation during Transcranial Fluorescence Brain Imaging

G. Molodij, I. Meglinski, A. Sdobnov, Y. Kuznetsov, A. Harmelin, V. Kalchenko

The paper introduces a Fourier Kappa-Omega filter to stabilize fast dynamic image sequences in transcranial fluorescence brain imaging, validated on mouse data and simulations.

bioRxiv · Oct 1, 2019Bioengineering

Overcoming insecticide resistance through computational inhibitor design

G. Correy, D. Zaidman, A. Harmelin, S. Carvalho, P. D. Mabbitt, V. Calaora, P. J. James, A. C. Kotze, N. London, C. J. Jackson

The paper designs boronic acid inhibitors to overcome insecticide resistance by targeting carboxylesterases in pests, significantly enhancing insecticide efficacy and reducing usage.

bioRxiv · Jan 24, 2019Biochemistry