B. Dassa

Competitive fungal commensalism mitigates candidiasis pathology

This study identifies a fungal commensal that competes with Candida albicans to reduce its burden and mitigate candidiasis in mice.

Molecular mechanisms underlying the modulation of T-cell proliferation and cytotoxicity by immobilized CCL21 and ICAM1

This study investigates how a synthetic immune niche modulates T-cell proliferation and cytotoxicity, finding that these properties are negatively correlated and differentially regulated by activation mode.

Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas

This study investigates dual targeting of HDACs and MYC in H3-K27M pediatric gliomas, showing synergistic effects in reducing cell viability and tumor growth.

Spatio-temporal coherence of circadian clocks and gating of differentiation in Anabaena filaments

The paper investigates how circadian clocks regulate heterocyst differentiation and nitrogen fixation in Anabaena filaments under nitrogen deprivation.

Deciphering the involvement of the Hippo pathway co-regulators, YAP/TAZ in invadopodia formation and matrix degradation

This study investigates the role of YAP/TAZ in invadopodia formation and matrix degradation in cancer cells, finding they suppress invadopodia formation and enhance matrix degradation when inhibited.

Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage

This paper identifies kynurenic acid as a protective metabolite that enhances cardiac cell viability and mitochondrial function following ischemic damage.

Bacterial lifestyle switch in response to algal metabolites

This study identifies algal metabolites that drive a bacterial lifestyle switch from coexistence to pathogenicity, highlighting the role of dimethylsulfoniopropionate (DMSP) and benzoate in shaping microbial interactions.

H3-K27M-Mutant Nucleosomes Interact with MLL1 to Shape the Glioma Epigenetic Landscape

This study shows H3-K27M mutations alter chromatin marks by affecting PRC2 and MLL1 interactions, leading to bivalent chromatin and supporting glioma development.

Division of labor between YAP and TAZ in non-small cell lung cancer

This study identifies distinct roles for YAP and TAZ in NSCLC, showing YAP regulates cell cycle and TAZ regulates extracellular matrix, with differential impacts on growth and migration.