Author

R. Oren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

L. Fellus-Alyagor· 3 shared A. Harmelin· 2 shared E. Shema· 2 shared G. Ron· 2 shared N. Furth· 2 shared N. London· 2 shared A. A. Schaffer· 1 shared A. Plotnikov· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

L. Fellus-Alyagor

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas

D. Algranati, R. Oren, B. Dassa, L. Fellus-Alyagor, A. Plotnikov, H. Barr, A. Harmelin, N. London, G. Ron, N. Furth, E. Shema

This study investigates dual targeting of HDACs and MYC in H3-K27M pediatric gliomas, showing synergistic effects in reducing cell viability and tumor growth.

bioRxiv · Feb 5, 2024Cancer Biology

Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion

S. C. Shvefel, J. Pai, Y. Cao, L. Pal, R. Levy, W. Yao, K. Cheng, M. Zemanek, O. Bartok, C. Weller, Y. Yin, P. Du, E. Yakubovich, I. Orr, S. Ben-Dor, , Y. Samuels

The paper identifies Mif as a regulator of tumor immune evasion in low intra-tumor heterogeneity melanoma by analyzing single-cell RNA sequencing data and validating in patient data.

bioRxiv · Nov 29, 2023 · PreprintCancer Biology

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

N. Harpaz, T. Mittelman, O. Beresh, O. Griess, N. Furth, T. M. Salame, R. Oren, L. Fellus-Alyagor, A. Harmelin, S. Alexandrescu, J. G. Marques, M. G. Filbin, G. Ron, E. Shema

The paper uses CyTOF to analyze histone modifications in DIPG tumors, identifying two epigenetically distinct subpopulations with differential proliferation and marker expression.

bioRxiv · Nov 2, 2021Cancer Biology

Cbp1, a rapidly evolving fungal virulence factor, forms an effector complex that drives macrophage lysis

D. Azimova, N. Herrera, L. Duvenage, M. Voorhies, B. C. English, J. C. Hoving, R. Oren, A. Sil

This paper identifies Cbp1 as a rapidly evolving fungal virulence factor that localizes to the host cell cytosol and forms a complex to drive macrophage lysis.

bioRxiv · Sep 16, 2021 · PreprintMicrobiology

Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivo

C. Dubiella, B. J. Pinch, D. Zaidman, T. D. Manz, E. Poon, S. He, E. Resnick, E. M. Langer, C. J. Daniel, H.-S. Seo, Y. Chen, S. B. Ficarro, Y. Jamin, X. Lian, S. Kibe, , N. London

Sulfopin, a selective Pin1 inhibitor, reduces tumor initiation and growth in neuroblastoma models by targeting c-Myc pathways.

bioRxiv · Mar 20, 2020 · PreprintCancer Biology