Author

A. Heinz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

K. Hiller· 2 shared A. Prigione· 1 shared A. Zink· 1 shared D. Jahn· 1 shared E. E. Wanker· 1 shared E. Latz· 1 shared F. Gorki· 1 shared F. I. Schmidt· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

K. Hiller

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3 papers

Recent·Most cited

Erythritol synthesis in human cells is elevated in response to oxidative stress and regulated by the non-oxidative pentose phosphate pathway

S. R. Ortiz, A. Heinz, K. Hiller, M. S. Field

This study identifies that erythritol synthesis in human cells is elevated under oxidative stress and regulated by non-oxidative PPP enzymes.

bioRxiv · Mar 7, 2022 · PreprintBiochemistry

Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome

M. S. J. Mangan, F. Gorki, K. Krause, A. Heinz, T. Ebert, D. Jahn, K. Hiller, V. Hornung, M. Mauer, F. I. Schmidt, R. Gerhard, E. Latz

The paper shows that C. difficile toxin B activates the NLRP3 inflammasome in human macrophages, not the Pyrin inflammasome, and that Pyrin activation can be restored with prolonged priming.

bioRxiv · Jul 7, 2021 · PreprintImmunology

Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay

A. Zink, J. Conrad, N. S. Telugu, S. Diecke, A. Heinz, E. E. Wanker, J. Priller, A. Prigione

The paper develops a high-throughput MNH assay to assess ethanol-induced toxicity in human dopaminergic neurons and identifies potential modulating drugs.

bioRxiv · Aug 12, 2020Cell Biology