Author

A. Helm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Fournier· 2 shared M. Durante· 2 shared A. Puspitasari· 1 shared A. Rehm· 1 shared B. Jakob· 1 shared C. Rellstab· 1 shared C. Schuy· 1 shared C. Totis· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBiophysics

C. Fournier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Induction of cytoplasmic dsDNA and cGAS-STING immune signaling after exposure of breast cancer cells to X-rays or high energetic carbon ions

C. Totis, N. B. Averbeck, B. Jakob, M. Schork, G. Volpi, D. F. Hintze, M. Durante, C. Fournier, A. Helm

This study shows carbon ions induce more cytosolic dsDNA and interferon-β in breast cancer cells than X-rays, enhancing innate immune signaling.

bioRxiv · Jul 23, 2024Biophysics

FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results

W. Tinganelli, O. Sokol, A. Puspitasari, A. Helm, P. Simoniello, C. Schuy, S. Lerchl, D. Eckert, J. Oppermann, A. Rehm, S. Janssen, D. Engel, R. Moeller, R. Romano, C. Fournier, , U. Weber

This study shows that FLASH irradiation with carbon ions spares normal tissue and maintains tumor control in mice, similar to conventional dose-rate treatments.

bioRxiv · Jul 12, 2024Cancer Biology

The effect of recent habitat change on genetic diversity at putatively adaptive and neutral loci in Primula veris in semi-natural grasslands

S. Traeger, C. Rellstab, I. Reinula, N. Zemp, A. Helm, R. Holderegger, T. Aavik

This study examines how recent habitat changes in semi-natural grasslands affect genetic diversity at adaptive and neutral loci in Primula veris, finding higher diversity at adaptive loci in overgrown habitats.

bioRxiv · May 12, 2021 · PreprintPlant Biology