C. Fournier

Genetic network analysis uncovers spatial variation in diversity and connectivity of a species presenting a continuous distribution

The paper develops a framework combining genetic network analysis and population genetics to assess connectivity and diversity in woodland caribou with continuous distributions, revealing isolation by distance and genetic erosion at range boundaries.

Second generation of LNP based mRNA vaccine leads to a T-cell-inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

This study shows that second-generation LNPs (Lipidots(R)) enhance antitumor immunity by remodeling the tumor microenvironment and synergizing with PD-1/PD-L1 blockade to improve therapeutic outcomes in cold tumors.

Induction of cytoplasmic dsDNA and cGAS-STING immune signaling after exposure of breast cancer cells to X-rays or high energetic carbon ions

This study shows carbon ions induce more cytosolic dsDNA and interferon-β in breast cancer cells than X-rays, enhancing innate immune signaling.

FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results

This study shows that FLASH irradiation with carbon ions spares normal tissue and maintains tumor control in mice, similar to conventional dose-rate treatments.

Inter-phylum circulation of a beta-lactamase - encoding gene: a rare but observable event

The paper reports the first inter-phylum transfer of an ESBL-encoding gene, blaMUN-1, between Bacteroidota and Pseudomonadota, highlighting rare but possible horizontal gene transfer events.

A fast and reliable larval sampling method for improving the monitoring of fruit flies in soft and stone fruits

This paper introduces a new larval sampling method for monitoring fruit fly infestations, which is faster, more precise, and scalable than existing techniques.

Ripening dynamics revisited: an automated method to track the development of asynchronous berries on time-lapse images

This paper introduces an automated method to track individual grapevine berry development in time-lapse images, revealing asynchronous ripening dynamics with high accuracy.

PhenoTrack3D: an automatic high-throughput phenotyping pipeline to track maize organs over time

PhenoTrack3D tracks maize organ development over time using 3D+t reconstruction from images, validated on a large dataset with high accuracy.

Bacterial microcompartments for isethionate desulfonation in the taurine-degrading human-gut bacterium Bilophila wadsworthia

This study identifies bacterial microcompartments involved in taurine desulfonation in Bilophila wadsworthia, revealing their role in sulfite respiration and H2S production.

Tuning the immunostimulation properties of cationic lipid nanocarriers for nucleic acid delivery

This study investigates how cationic lipid nanocarriers affect macrophages and dendritic cells, showing that adjusting nucleic acid load can mitigate adverse immune responses.

X-ray Irradiation activates immune response in human T-lymphocytes by eliciting a Ca2+ signaling cascade

The paper shows X-ray irradiation triggers a Ca2+ signaling cascade in T-lymphocytes, leading to immune activation through NFAT nuclear translocation.

Phenomenal: An automatic open source library for 3D shoot architecture reconstruction and analysis for image-based plant phenotyping

Phenomenal provides an open-source library for automated 3D shoot architecture reconstruction and analysis from plant images across species and datasets.

HydroShoot: a functional-structural plant model for simulating hydraulic structure, gas and energy exchange dynamics of complex plant canopies under water deficit - application to grapevine (Vitis vinifera L.)

HydroShoot simulates canopy gas-exchange under water deficit by integrating shoot hydraulic structure and leaf energy budget, showing hydraulic structure is more critical for scaling leaf to canopy gas-exchange rates.