Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice
C. E. Hioe, G. Li, X. Liu, O. Tsahouridis, X. He, M. Funaki, J. Klingler, A. F. Tang, R. Feyznezhad, D. W. Heindel, X.-H. Wang, D. A. Spencer, G. Hu, N. Satija, J. Prevost, , L. Su
This study shows that non-neutralizing antibodies targeting HIV-1 envelope regions reduce mucosal infection and virus burden in humanized mice through Fc-mediated effector functions.
bioRxiv · May 24, 2021Immunology