ImmunologybioRxiv
Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice
C. E. Hioe, G. Li, X. Liu…·L. Su
This study shows that non-neutralizing antibodies targeting HIV-1 envelope regions reduce mucosal infection and virus burden in humanized mice through Fc-mediated effector functions.
DOI 10.1371/journal.ppat.1010183