BiochemistrybioRxiv
RNA-binding proteins with mixed charge domains self-assemble and aggregate in Alzheimer’s Disease
I. Bishof, E. B. Dammer, D. M. Duong…·N. T. Seyfried
This study identifies mixed charge domains in RNA-binding proteins that self-assemble and aggregate in Alzheimer’s Disease, linking them to Tau co-aggregation and nuclear RNA granule formation.
DOI 10.1074/jbc.ra118.001747