A. J. Eisch

Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity

This study shows that increasing lateral entorhinal cortex-dentate gyrus circuit activity in mice improves behavioral pattern separation and cognitive flexibility, along with increased neurogenesis.

Effects of a 33-ion sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure

This study examines the effects of 33-ion galactic cosmic ray analog exposure on male mouse behavior and evaluates CDDO-EA as a potential countermeasure, finding no effect on exploration or anxiety but deficits in social novelty preference.

Multi-domain touchscreen-based cognitive assessment of C57BL/6J female mice shows whole body exposure to 56Fe particle space radiation in maturity improves discrimination learning yet impairs stimulus-response habit learning

This study shows that whole-body exposure to 56Fe radiation in mature female C57BL/6J mice improves hippocampal-dependent discrimination learning but impairs striatal-dependent rule-based learning.

Does chronic systemic injection of the DREADD agonists clozapine-N-oxide or compound 21 change behavior relevant to locomotion, exploration, anxiety, and depression in male non-DREADD-expressing mice?

This study investigates whether chronic systemic injections of DREADD agonists CNO or C21 alter behavior in non-DREADD-expressing mice, finding minimal behavioral effects.

Maternal Continuous Oral Oxycodone Self-Administration Alters Pup Affective/Social Communication but not Spatial Learning or Sensory-Motor Function