Author

A. J. Garvin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. K. Walker· 2 shared H. L. Mackay· 2 shared H. R. Stone· 2 shared J. R. Morris· 2 shared K. Starowicz· 2 shared R. M. Densham· 2 shared A. Aitsiankova· 1 shared A. S. Chauhan· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. K. Walker

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.

H. L. Mackay, H. R. Stone, K. Ellis, G. Ronson, K. Starowicz, A. J. Garvin, P. Van Eijk, A. Aitsiankova, S. Vijayendran, J. Beesley, E. Petermann, E. Brown, R. M. Densham, S. H. Reed, F. Dobbs, , J. R. Morris

This study identifies USP50 as a ubiquitin-binding protein that regulates helicase and nuclease activities during DNA replication to prevent fork collapse and maintain genomic stability.

bioRxiv · Jan 10, 2024Cancer Biology

The deSUMOylase SENP2 coordinates homologous recombination and non-homologous end joining by independent mechanisms.

A. J. Garvin, A. K. Walker, R. M. Densham, A. S. Chauhan, H. R. Stone, H. L. MacKay, M. Jamshad, K. Starowicz, M. Daza-Martin, J. R. Morris

This study identifies SENP2 as a deSUMOylase that differentially regulates homologous recombination and non-homologous end joining through distinct mechanisms, impacting DSB repair and radioresistance.

Genes & Development · Feb 22, 2019Peer-reviewedCell Biology