PathologybioRxiv
TDP-43-stratified single-cell proteomic profiling of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis
A. J. Guise, S. A. Misal, R. Carson…·R. T. Kelly
This study uses single-cell proteomics to analyze motor neurons from ALS patients, identifying protein changes linked to TDP-43 pathology.
DOI 10.1016/j.celrep.2023.113636