Author

A. J. Plodkowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

A. Chow· 2 shared H. Rizvi· 2 shared M. D. Hellmann· 2 shared T. Merghoub· 2 shared A. J. Minn· 1 shared A. J. Schoenfeld· 1 shared A. Quintanal-Villalonga· 1 shared A. T. Satpathy· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Chow

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Author profile →

2 papers

Recent·Most cited

Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade

J. A. Pai, A. Chow, J. Sauter, M. Mattar, H. Rizvi, H. J. Woo, N. Shah, F. Uddin, A. Quintanal-Villalonga, J. M. Chan, P. Manoj, V. Allaj, M. Baine, J. E. Chaft, A. J. Plodkowski, , M. D. Hellmann

This study uses scTCR/RNA-seq to analyze T cell dynamics in lung cancer patients before and after ICB, finding regional heterogeneity and clonal persistence associated with clinical responses.

bioRxiv · Sep 27, 2021 · PreprintImmunology

Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

D. Memon, H. Rizvi, G. Fromm, J. Lihm, A. J. Schoenfeld, J. L. Sauter, J. Luo, A. Chow, U. K. Bhanot, C. McCarthy, D. Ye, C. M. Vanderbilt, C. Liu, M. Abu-Akeel, A. J. Plodkowski, , M. D. Hellmann

This study characterizes clinical and molecular features of acquired resistance to PD-(L)1 blockade in NSCLC, identifying persistent inflammation and dysfunctional IFN signaling as key features.

bioRxiv · Jul 21, 2021Cancer Biology