Author

M. Mattar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Assay:proteomics· 2 Research Focus:trajectory inference· 2

Frequent Co-Authors

A. Chow· 3 shared A. Quintanal-Villalonga· 3 shared C. M. Rudin· 3 shared J. M. Chan· 3 shared T. Sen· 3 shared V. Allaj· 3 shared E. de Stanchina· 2 shared F. Uddin· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

A. Chow

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD39 Identifies Tumor-Reactive CD8 T cells in Patients With Lung Cancer

A. Chow, F. Z. Uddin, L. Mangarin, H. Rizvi, A. Dobrin, S. E. Tischfield, A. Quintanal-Villalonga, J. M. Chan, N. S. Shah, V. Allaj, P. Manoj, M. Mattar, M. Meneses, M. Liu, R. Landau, , C. M. Rudin

This study identifies CD39 as a marker for tumor-reactive CD8 T cells in lung cancer, showing its association with clinical outcomes and response to immune checkpoint therapy.

bioRxiv · Jan 24, 2022 · PreprintImmunology

Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade

J. A. Pai, A. Chow, J. Sauter, M. Mattar, H. Rizvi, H. J. Woo, N. Shah, F. Uddin, A. Quintanal-Villalonga, J. M. Chan, P. Manoj, V. Allaj, M. Baine, J. E. Chaft, A. J. Plodkowski, , M. D. Hellmann

This study uses scTCR/RNA-seq to analyze T cell dynamics in lung cancer patients before and after ICB, finding regional heterogeneity and clonal persistence associated with clinical responses.

bioRxiv · Sep 27, 2021 · PreprintImmunology

Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

P. M. R. Pereira, K. Mandleywala, S. Monette, M. Lumish, K. M. Tully, M. Cornejo, A. Mauguen, A. Ragupathi, M. Mattar, Y. Y. Janjigian, J. S. Lewis

This paper identifies CAV1 as a biomarker for trastuzumab efficacy in HER2-positive gastric cancer and shows that statin use enhances antibody therapy response.

bioRxiv · Jul 13, 2021 · PreprintCancer Biology

Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer

J. M. Chan, A. Quintanal-Villalonga, V. Gao, Y. Xie, V. Allaj, O. Chaudhary, I. Masilionis, J. Egger, A. Chow, T. Walle, M. Mattar, D. V. Yarlagadda, J. L. Wang, F. Uddin, M. Offin, , C. M. Rudin

The paper profiles single-cell transcriptomes of SCLC subtypes to identify novel tumor and myeloid subpopulations and their associations with metastasis and immune microenvironment changes.

bioRxiv · Dec 1, 2020Cancer Biology