A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
T. K. Tan, P. Rijal, R. Rahikainen, A. Keeble, L. Schimanski, S. Hussain, R. Harvey, J. Hayes, J. Edwards, R. McLean, V. Martini, M. Pedrera, N. Thakur, C. Conceicao, I. Dietrich, , R. Owens
This study develops a vaccine candidate using SpyCatcher technology to display the SARS-CoV-2 RBD, showing strong neutralizing antibody responses in mice and pigs.
bioRxiv · Aug 31, 2020Immunology