Author

C. Browning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:plant (other)· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Burman· 2 shared A. S. Asfor· 2 shared B. Charleston· 2 shared C. Chiu· 2 shared C. Conceicao· 2 shared D. Bailey· 2 shared D. Bialy· 2 shared E. Tchilian· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Burman

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Author profile →

3 papers

Recent·Most cited

Mechanism of glycogen synthase inactivation and interaction with glycogenin

L. Marr, D. Biswas, L. A. Daly, C. Browning, S. Vial, D. P. Maskell, C. Hudson, J. Pollard, J. Bertrand, N. A. Ranson, H. Khatter, C. E. Eyers, K. Sakamoto, E. Zeqiraj

The paper describes the cryo-EM structure of phosphorylated glycogen synthase and its interaction with glycogenin, revealing mechanisms of GS autoinhibition and regulation.

bioRxiv · Nov 14, 2021Biochemistry

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

T. K. Tan, P. Rijal, R. Rahikainen, A. Keeble, L. Schimanski, S. Hussain, R. Harvey, J. Hayes, J. Edwards, R. McLean, V. Martini, M. Pedrera, N. Thakur, C. Conceicao, I. Dietrich, , R. Owens

This study develops a vaccine candidate using SpyCatcher technology to display the SARS-CoV-2 RBD, showing strong neutralizing antibody responses in mice and pigs.

bioRxiv · Aug 31, 2020Immunology

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

S. P. Graham, R. K. McLean, A. J. Spencer, S. Belij-Rammerstorfer, D. Wright, M. Ulaszewska, J. C. Edwards, J. W. P. Hayes, V. Martini, N. Thakur, C. Conceicao, I. Dietrich, H. Shelton, R. Waters, A. Ludi, , T. Lambe

This study evaluates the immunogenicity of single and booster doses of the ChAdOx1 nCoV-19 vaccine in mice and pigs, finding that a booster significantly enhances antibody responses, especially in pigs.

bioRxiv · Jun 20, 2020Immunology