Author

A. Kiltie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hampson· 1 shared A. N. Singh· 1 shared A. Ruggiano· 1 shared B. Vaz· 1 shared C. K. Then· 1 shared G. Higgins· 1 shared G. Rodriguez-Berriguete· 1 shared I. Torrecilla· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Hampson

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2 papers

Recent·Most cited

Association of Bacteroides acidifaciens relative abundance with high-fibre diet-associated radiosensitisation

C. K. Then, S. Paillas, X. Wang, A. Hampson, A. Kiltie

This study shows that a soluble high-fibre diet enhances radiosensitivity of bladder cancer xenografts in mice, associated with increased Bacteroides acidifaciens abundance and microbial metabolites.

bioRxiv · Jun 6, 2020Cancer Biology

SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

B. Vaz, A. Ruggiano, M. Popovic, G. Rodriguez-Berriguete, S. Kilgas, A. N. Singh, I. Torrecilla, G. Higgins, A. Kiltie, K. Ramadan

This study identifies SUMO-1 modification of DNA-protein crosslinks (DPCs) as a mechanism that promotes SPRTN proteolysis over homologous recombination, preventing genomic instability.

bioRxiv · Feb 14, 2020 · PreprintCell Biology