Use of IFNγ/IL10 ratio for stratification of hydrocortisone therapy in patients with septic shock
R. Koenig, A. Kolte, O. Ahlers, M. Oswald, D. Roell, G. Dimopoulos, I. Tsangaris, E. Antoniadou, H. Bogatsch, M. Loeffler, C. L. Sprung, M. Singer, F. Brunkhorst, M. Oppert, H. Gerlach, , M. Bauer
This paper identifies the IFNγ/IL10 ratio as a biomarker to guide hydrocortisone therapy in septic shock, showing improved survival when treatment aligns with the ratio's prediction.
bioRxiv · Dec 21, 2018Immunology