GlnA3Mt is able to glutamylate spermine but it is not essential for the detoxification of spermine in Mycobacterium tuberculosis
S. Krysenko, C. S. Emani, M. Bäuerle, M. Oswald, A. Kulik, C. Meyners, D. Hillemann, M. Merker, I. Wohlers, F. Hausch, H. Brötz-Oesterhelt, A. Mitulski, N. Reiling, W. Wohlleben
The paper shows that GlnA3Mt in M. tuberculosis can glutamylate spermine but is not essential for spermine detoxification, with efflux pumps playing a compensatory role.
bioRxiv · Dec 14, 2023 · PreprintMicrobiology