Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic andtargetable tissue states
O. Al-Dalahmah, M. Argenziano, A. Kannan, A. Mahajan, J. Furnari, F. Paryani, D. Boyett, A. Save, N. Humala, F. Khan, J. Li, H. Lu, Y. Sun, J. Tuddenham, a. r. goldberg, , P. Canoll
The paper identifies three tissue states in glioblastoma microenvironments using snRNAseq and spatial transcriptomics, linking them to metabolic pathways and clinical outcomes.
bioRxiv · Jul 6, 2021Pathology