Functional Biosynthetic Stereodivergence in a Gene Cluster via a Dihydrosydnone N-oxide
J. Ren, A. Mathew, M. Rodriguez Garcia, T. Kohler, O. Blacque, A. Linden, L. Eberl, S. Sieber, K. Gademann
The paper investigates a gene cluster that produces both enantiomerically pure and racemic metabolites through a stereodivergent pathway involving a dihydrosydnone N-oxide intermediate.
bioRxiv · Apr 29, 2024Biochemistry