Author

A. Lopatina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:metagenomics· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bernheim· 2 shared A. Leavitt· 2 shared A. Millman· 2 shared G. Amitai· 2 shared R. Sorek· 2 shared S. Melamed· 2 shared A. J. Probst· 1 shared A. Kacen· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

A. Bernheim

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Author profile →

3 papers

Recent·Most cited

An expanding arsenal of immune systems that protect bacteria from phages

A. Millman, S. Melamed, A. Leavitt, S. Doron, A. Bernheim, J. Hör, A. Lopatina, G. Ofir, D. Hochhauser, A. Stokar-Avihail, N. Tal, S. Sharir, M. Voichek, Z. Erez, J. L. M. Ferrer, , R. Sorek

This study identifies 21 new bacterial defense systems against phages through genomic analysis and experiments, revealing novel protein domains and toxin-antitoxin mechanisms involved in anti-phage immunity.

bioRxiv · May 11, 2022Microbiology

Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion

J. Garb, A. Lopatina, A. Bernheim, M. Zaremba, V. Siksnys, S. Melamed, A. Leavitt, A. Millman, G. Amitai, R. Sorek

The paper shows DSR proteins deplete NAD+ during phage infection, inhibiting propagation, and identifies SIR2 domains as effector NADases in bacterial immunity.

bioRxiv · Dec 14, 2021Microbiology

Host-associated phages disperse across the extraterrestrial analogue Antarctica

J. Rahlff, T. L. V. Bornemann, A. Lopatina, K. Severinov, A. J. Probst

The paper tracks host-associated phages across Antarctica using metagenomic data, finding long-distance dispersal of Ralstonia phages with implications for Astrobiology and Planetary Protection.

bioRxiv · Nov 9, 2021Microbiology