Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly
The paper shows bacteria use ubiquitin-like protein conjugation to block phage assembly and infectivity.
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4 papers
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The paper shows bacteria use ubiquitin-like protein conjugation to block phage assembly and infectivity.
A. Millman, S. Melamed, A. Leavitt…·R. Sorek
This study identifies 21 new bacterial defense systems against phages through genomic analysis and experiments, revealing novel protein domains and toxin-antitoxin mechanisms involved in anti-phage immunity.
J. Hör, J. Jung, S. Đurica-Mitic…·J. Vogel
The paper introduces INRI-seq, a cell-free Ribo-seq method to study translation initiation and off-target effects of antisense inhibitors in E. coli.
J. Hör, S. Di Giorgio, M. Gerovac…·J. Vogel
The paper uses Grad-seq to map RNA/protein complexes in E. coli, identifying new interactions and reclassifying RNA functions.