Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
B. Duncan-Lowey, N. Tal, A. G. Johnson, S. Rawson, M. L. Mayer, S. Doron, A. Millman, S. Melamed, T. Fedorenko, A. Kacen, G. Amitai, R. Sorek, P. J. Kranzusch
The paper determines the cryo-EM structure of the RADAR complex, showing RdrB targets mononucleotides and catalyzes ATP-to-ITP conversion to limit phage replication.
Cell · Mar 1, 2023Peer-reviewedBiochemistry
A. Millman, S. Melamed, A. Leavitt, S. Doron, A. Bernheim, J. Hör, A. Lopatina, G. Ofir, D. Hochhauser, A. Stokar-Avihail, N. Tal, S. Sharir, M. Voichek, Z. Erez, J. L. M. Ferrer, , R. Sorek
This study identifies 21 new bacterial defense systems against phages through genomic analysis and experiments, revealing novel protein domains and toxin-antitoxin mechanisms involved in anti-phage immunity.
bioRxiv · May 11, 2022Microbiology
M. LeRoux, S. Srikant, M. L. Littlehale, G. Teodoro, S. Doron, M. Badiee, A. Leung, R. Sorek, M. T. Laub
This study identifies DarTG toxin-antitoxin systems in E. coli that defend against phage by ADP-ribosylating viral DNA, with phages evolving resistance through DNA polymerase or anti-DarT factors.
bioRxiv · Sep 27, 2021 · PreprintMicrobiology
S. Doron, N. Lampl, A. Savidor, C. Katina, A. Gabashvili, Y. Levin, S. Rosenwasser
SPEAR quantifies cysteine oxidation states and protein abundance in Arabidopsis under steady-state and oxidative stress, revealing widespread redox effects on cellular functions.
bioRxiv · Jun 17, 2021Biochemistry
G. Ofir, E. Herbst, M. Baroz, D. Cohen, A. Millman, S. Doron, N. Tal, D. B. A. Malheiro, S. Malitsky, G. Amitai, R. Sorek
This study identifies a bacterial antiviral pathway using TIR domains to produce a signaling molecule that triggers cell death via NAD depletion.
bioRxiv · Jan 6, 2021Microbiology