Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-induced Myeloid-Derived Suppressor Cells
W. Huang, Y. Liu, A. Luz, M. Berrong, J. Meyer, Y. Zou, E. Swann, P. Sundaramoorthy, Y. Kang, S. Jauhari, W. Lento, N. Chao, L. Racioppi
This study identifies CaMKK2 as a regulator of MDSC expansion, showing its inhibition reduces tumor growth and enhances antitumor immunity.
bioRxiv · Jul 28, 2021Immunology