BiophysicsbioRxiv
Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates fibril-induced cellular stress.
G. Jain, M. Trombetta-Lima, I. Matlahov…·P. C. A. van der Wel
This study shows that curcumin modulates huntingtin aggregation, reducing cellular stress by altering fibril structure and metabolic properties.
DOI 10.1038/s41467-025-58691-9