BiophysicsbioRxiv
Structural modeling of the hERG potassium channel and associated drug interactions
J. Maly, A. M. Emigh, K. R. DeMarco…·V. Yarov-Yarovoy
This study uses Rosetta to model structural changes in hERG channels caused by mutations and drug interactions, revealing conformational shifts and binding mechanisms.
DOI 10.3389/fphar.2022.966463