BiochemistrybioRxiv
Structure of the Human Signal Peptidase Complex Reveals the Determinants for Signal Peptide Cleavage
A. M. Liaci, B. Steigenberger, S. Tamara…·F. Foerster
The paper determines the atomic structures of human signal peptidase complex paralogs and identifies how their architecture enables specific recognition and cleavage of signal peptides.
DOI 10.1016/j.molcel.2021.07.031