Author

A. M. Murphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Organism:Arabidopsis· 2 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

J. P. Carr· 2 shared S. Crawshaw· 2 shared A. P. Baldo· 1 shared C. Gibson· 1 shared C. Vasquez· 1 shared D. Nietlispach· 1 shared J. C. Tardiff· 1 shared J. Jimenez· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPlant Biology

J. P. Carr

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3 papers

Recent·Most cited

Investigating the interactions of the cucumber mosaic virus 2b protein with the viral 1a replicase component and the cellular RNA silencing factor Argonaute 1

S. Crawshaw, A. M. Murphy, P. J. E. Rowling, D. Nietlispach, L. S. Itzhaki, J. P. Carr

The paper investigates how the CMV 2b protein interacts with AGO1 and 1a protein, finding that residues 56-60 influence these interactions but no single residue is solely responsible.

bioRxiv · Mar 18, 2024Plant Biology

Strain-specific differences in the interactions of the cucumber mosaic virus 2b protein with the viral 1a and host Argonaute 1 proteins

S. Crawshaw, L. G. Watt, A. M. Murphy, J. P. Carr

The paper investigates strain-specific differences in how CMV 2b proteins interact with viral 1a and host AGO1 proteins, affecting miRNA-mediated mRNA cleavage and virus resistance.

bioRxiv · Aug 31, 2023Plant Biology

The HCM-Linked Mutation Arg92Leu in TNNT2 Allosterically Alters the cTnC-cTnI Interface and Disrupts the PKA-mediated Regulation of Myofilament Relaxation

M. L. Lynn, J. Jimenez, R. L. Castillo, M. M. Klass, C. Vasquez, A. P. Baldo, C. Gibson, A. M. Murphy, J. C. Tardiff

This paper investigates how the HCM-linked mutation Arg92Leu in TNNT2 alters the cTnC-cTnI interface, impairing PKA access and causing early diastolic dysfunction.

bioRxiv · Jul 18, 2023 · PreprintBiophysics