BiophysicsbioRxiv
The mechanistic basis for chromatin invasion and remodeling by the yeast pioneer transcription factor Rap1
M. Mivelaz, A.-M. Cao, S. Kubik…·B. Fierz
This study reveals how the yeast pioneer transcription factor Rap1 invades and remodels chromatin by opening fiber structure and collaborating with RSC to destabilize promoter nucleosomes.
DOI 10.1016/j.molcel.2019.10.025