Author

A. Main

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

G. L. Smith· 2 shared G. S. Baillie· 2 shared W. Fuller· 2 shared A. Boguslavskyi· 1 shared A. C. Rankin· 1 shared A. Rankin· 1 shared C.-w. S. Kuo· 1 shared F. L. Burton· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

G. L. Smith

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

zDHHC5 expression is increased in cardiac hypertrophy and reduced in heart failure but this does not correlate with changes in substrate palmitoylation

A. Main, A. Boguslavskyi, J. Howie, C.-w. S. Kuo, A. Rankin, F. L. Burton, G. L. Smith, R. Hajjar, G. S. Baillie, K. S. Campbell, M. J. Shattock, W. Fuller

This study examines zDHHC5 expression and palmitoylation changes in cardiac diseases, finding increased zDHHC5 in hypertrophy and decreased in failure, with no correlation to substrate palmitoylation changes.

bioRxiv · Aug 19, 2022Biochemistry

Cardiac myosin binding protein-C palmitoylation is associated with increased myofilament affinity, reduced myofilament Ca2+ sensitivity and is increased in ischaemic heart failure.

A. Main, G. N. Milburn, R. M. Balesar, A. C. Rankin, G. L. Smith, K. Campbell, G. S. Baillie, J. van der Velden, W. Fuller

This study identifies palmitoylation of cMyBP-C in cardiac myofilaments, showing it reduces Ca2+ sensitivity and is altered in heart failure.

bioRxiv · Jun 21, 2022 · PreprintCell Biology