Author

A. Malek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gross· 1 shared B. Györffy· 1 shared B. Klinger· 1 shared B. Küster· 1 shared C. Sers· 1 shared C. W. Choate· 1 shared D. A. Wyatt· 1 shared F. Iqbal· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Gross

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Up-regulated transcriptional regulators in mutant RAS gene signatures: a time-resolved multi-omics study in generic epithelial cell models

K. Kasack, P. Metzger, H. Koch, B. Klinger, A. Malek, O. Tchernitsa, A. Gross, W. Wruck, B. Györffy, B. Küster, C. Sers, M. Börries, R. Schäfer

This study identifies HMGA2 as a master regulator of mutant RAS-driven gene expression by analyzing time-resolved transcriptome and proteome changes in epithelial cells.

bioRxiv · Jun 4, 2024 · PreprintCancer Biology

Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery

M. W. Sedovy, X. Leng, F. Iqbal, M. C. Renton, M. Leaf, K. Roberts, A. Malek, W. S. Arnold, D. A. Wyatt, C. W. Choate, J. F. Rowe, J. W. Baker, S. R. Johnstone, M. Joseph

This study compares heparinized saline and blood solutions for preserving saphenous vein endothelium during coronary bypass graft preparation, finding blood better preserves endothelial integrity and reduces oxidative stress.

bioRxiv · Aug 25, 2023Physiology