Author

H. Koch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Immunology· 2 Biochemistry· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Approach:experimental assay· 5 Assay:metagenomics· 4 Research Focus:cell type annotation· 3 Research Focus:ecology & biodiversity· 3 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2

Frequent Co-Authors

J. Frank· 2 shared M. A. H. J. van Kessel· 2 shared M. S. M. Jetten· 2 shared P. C. Stevenson· 2 shared S. Lücker· 2 shared S. Luecker· 2 shared A. B. Mundinger· 1 shared A. Carfi· 1 shared

Activity by Year

2018-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersMicrobiology

J. Frank

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11 papers

Recent·Most cited

Unveiling unique microbial nitrogen cycling and novel nitrification drivers in coastal Antarctica

P. Han, X. Tang, H. Koch, X. Dong, L. Hou, D. Wang, Q. Zhao, Z. Li, M. Liu, S. Luecker, G. Shi

This study identifies unique microbial nitrogen cycling mechanisms in coastal Antarctica, highlighting the role of comammox Nitrospira in nitrification.

bioRxiv · Nov 19, 2023Microbiology

mRNA delivery of dimeric human IgA protects mucosal tissues from bacterial infection

C. E. Deal, A. F. Richards, T. Yeung, M. J. Maron, Z. Wang, Y.-T. Lai, B. R. Fritz, S. Himansu, E. Narayanan, D. Liu, R. Koleva, S. Licht, C. J. Hsiao, I. L. Rajlic, H. Koch, , O. J. Plante

The paper demonstrates that mRNA-delivered human IgA can protect mucosal tissues from bacterial infection by trafficking to mucosal sites and limiting bacterial invasion.

bioRxiv · Jan 3, 2023 · PreprintImmunology

Investigating the chemolithoautotrophic and formate metabolism of Nitrospira moscoviensis by constraint-based metabolic modeling and 13C-tracer analysis

C. E. Lawson, A. B. Mundinger, H. Koch, T. B. Jacobson, C. A. Weathersby, M. S. Jetten, M. Pabst, D. Amador-Noguez, D. R. Noguera, K. McMahon, S. Lücker

This study reconstructs a genome-scale metabolic model of Nitrospira moscoviensis and validates it using proteomics, 13C-tracer, and metabolomic analysis to elucidate its autotrophic and formate metabolism.

bioRxiv · Feb 18, 2021Microbiology

Agri-environment nectar chemistry suppresses parasite social epidemiology in an important pollinator

A. J. Folly, H. Koch, I. W. Farrell, P. C. Stevenson, M. J. F. Brown

This study shows that caffeine in nectar reduces Nosema bombi infection in bumblebees and impacts social disease transmission.

bioRxiv · Jan 30, 2021Ecology

Pollen sterols are associated with phylogenetics and environment but not with pollinators

P. Zu, H. Koch, O. Schwery, S. Pironon, C. Phillips, I. Ondo, I. Farrell, W. D. Nes, E. Moore, G. Wright, D. I. Farman, P. C. Stevenson

This study quantifies pollen phytosterols across 122 plant species and finds phylogenetic clustering and environmental adaptation but no link to pollinator guilds.

bioRxiv · Dec 18, 2020Biochemistry

Sweet and magnetic: Succession and CAZyme expression of marine bacterial communities encountering a mix of alginate and pectin particles

C. Bunse, H. Koch, S. Breider, M. Simon, M. Wietz

The paper studies marine bacterial communities interacting with mixed alginate and pectin particles, finding similar dynamics on both substrates with distinct functional adaptations.

bioRxiv · Dec 8, 2020Microbiology

Exploring the upper pH limits of nitrite oxidation: diversity, ecophysiology, and adaptive traits of haloalkalitolerant Nitrospira

A. Daebeler, K. Kitzinger, H. Koch, C. W. Herbold, M. Steinfeder, J. Schwarz, T. Zechmeister, S. M. Karst, M. Albertsen, P. H. Nielsen, M. Wagner, H. Daims

This study identifies haloalkalitolerant Nitrospira species in extreme pH lakes, revealing their diversity and adaptive traits for nitrite oxidation at high pH.

The ISME Journal · Jul 24, 2020Peer-reviewedMicrobiology

Enrichment and physiological characterization of a novel comammox Nitrospira indicates ammonium inhibition of complete nitrification

D. Sakoula, H. Koch, J. Frank, M. S. M. Jetten, M. A. H. J. van Kessel, S. Lücker

This study enriches and characterizes a novel comammox Nitrospira species, revealing its high ammonia affinity and ammonium inhibition, suggesting niche differentiation based on ammonium tolerance.

bioRxiv · Jun 8, 2020Microbiology

Metagenomic profiling of ammonia- and methane-oxidizing microorganisms in a Dutch drinking water treatment plant

L. Poghosyan, H. Koch, J. Frank, M. A. H. J. van Kessel, G. Cremers, T. van Alen, M. S. M. Jetten, H. J. M. Op den Camp, S. Luecker

This study profiles ammonia- and methane-oxidizing microorganisms in a Dutch drinking water treatment plant using metagenomic sequencing, identifying key microbial taxa and their distribution across different filtration stages.

bioRxiv · May 19, 2020 · PreprintMicrobiology

Maximum likelihood estimation of species trees from gene trees in the presence of ancestral population structure

H. Koch, M. DeGiorgio

This paper introduces TASTI, a maximum likelihood method for inferring species trees from gene trees under ancestral population structure, showing improved accuracy with more gene trees.

bioRxiv · Jul 14, 2019Evolutionary Biology

powerTCR: a model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoire

H. Koch, D. Starenki, S. J. Cooper, R. M. Myers, Q. Li

The paper introduces a model-based method to analyze T cell receptor repertoire clone size distributions and applies it to datasets to identify differences across biological conditions.

bioRxiv · Oct 22, 2018Immunology