Author

K. Kasack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Eggert· 1 shared A. G. Henssen· 1 shared A. Gross· 1 shared A. Malek· 1 shared A. Szymansky· 1 shared B. Györffy· 1 shared B. Klinger· 1 shared B. Küster· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Eggert

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2 papers

Recent·Most cited

Up-regulated transcriptional regulators in mutant RAS gene signatures: a time-resolved multi-omics study in generic epithelial cell models

K. Kasack, P. Metzger, H. Koch, B. Klinger, A. Malek, O. Tchernitsa, A. Gross, W. Wruck, B. Györffy, B. Küster, C. Sers, M. Börries, R. Schäfer

This study identifies HMGA2 as a master regulator of mutant RAS-driven gene expression by analyzing time-resolved transcriptome and proteome changes in epithelial cells.

bioRxiv · Jun 4, 2024 · PreprintCancer Biology

Enhancer hijacking determines intra- and extrachromosomal circular MYCN amplicon architecture in neuroblastoma

K. Helmsauer, M. Valieva, S. Ali, R. Chamorro Gonzalez, R. Schoepflin, C. Roeefzaad, Y. Bei, H. Dorado Garcia, E. Rodriguez-Fos, M. Puiggros, V. Heinrich, M. Robson, K. Kasack, K. Haase, L. P. Kuschel, , R. P. Koche

The paper identifies two distinct MYCN amplicon structures in neuroblastoma, showing how enhancer hijacking compensates for loss of local regulatory elements.

bioRxiv · Dec 20, 2019Cancer Biology